O-Mugi Lab ｜ Barley Topics

Intake of BARLEYmax increases butyric acid-producing bacteria and butyric acid levels in the human intestines.

Fiber-Rich Barley Increases Butyric Acid-Producing Bacteria in the Human Gut Microbiota
Metabolites 11, 8, 559, 2021

β-glucan-rich barley enhances immune function, stimulates sIgA secretion and IL-10 expression

Ingestion of High β-Glucan Barley Flour Enhances the Intestinal Immune System of Diet-Induced Obese Mice by Prebiotic Effects
Nutrients 13, 3, 907, 2021

Beta-glucan-rich Barley improves glucose tolerance via increased GLP-1 secretion

High β-Glucan Barley Supplementation Improves Glucose Tolerance by Increasing GLP-1 Secretion in Diet-Induced Obesity Mice
Nutrients 13, 2, 527, 2021

Low molecular weight barley β-glucan improves glucose and lipid metabolism through its prebiotic effect

Low Molecular Weight Barley β-Glucan Affects Glucose and Lipid Metabolism by Prebiotic Effects
Nutrients 13, 1, 130, 2021

Barley improves lipid metabolism in liver and adipose tissue at the level of gene expression

Effects of β-glucan Rich Barley Flour on Glucose and Lipid Metabolism in the Ileum, Liver, and Adipose Tissues of High-Fat Diet Induced-Obesity Model Male Mice Analyzed by DNA Microarray
Nutrients 12, 11, 3546, 2020

Barley β-glucan improves glucose and lipid metabolism even when moderately reduced in molecular weight

Effects of barley β-glucan with various molecular weights partially hydrolyzed by endogenous β-glucanase on glucose tolerance and lipid metabolism in mice
Cereal Chemistry Aug 4, 2020

The molecular weight of oat beta-glucan does not affect the incremental glucose area-under-the–curve (iAUC)

Effect of Varying Molecular Weight of Oat β-Glucan Taken just before Eating on Postprandial Glycemic Response in Healthy Humans
Nutrients 12, 8, E2275, 2020

Oats and rye regulate lipid metabolism through different mechanisms and improve liver function and intestinal barrier function.

Dietary Fiber from Oat and Rye Brans Ameliorate Western Diet–Induced Body Weight Gain and Hepatic Inflammation by the Modulation of Short-Chain Fatty Acids, Bile Acids, and Tryptophan Metabolism
Mol Nutr Food Res e1900580, 2020

The synbiotics-effect of barley beta-glucan and lactic acid bacteria
Activation of AMPK and Inhibition of Fat Accumulation

A synbiotic consisting of Lactobacillus plantarum S58 and hull-less barley β-glucan ameliorates lipid accumulation in mice fed with a high-fat diet by activating AMPK signaling and modulating the gut microbiota
Carbohydr Polym 243, 116398, 2020

The effect of whole grains on glycemic control is higher at lower processing levels

Whole-Grain Processing and Glycemic Control in Type 2 Diabetes: A Randomized Crossover Trial
Diabetes Care dc200263, 2020

Dietary fiber intake extends life expectancy of diabetics
35% reduction in risk of death from 19g to 35g per day

Dietary fibre and whole grains in diabetes management: Systematic review and meta-analyses
PLoS Med 17, 3, e1003053, 2020

Grain fiber lowers risk of developing diabetes.
Evidence rated "high" in Umbrella Review

Role of diet in type 2 diabetes incidence: umbrella review of meta-analyses of prospective observational studies
BMJ 365, l2368, 2019

Fiber intake during pregnancy prevents obesity in offspring mice.
Short-chain fatty acids normalize metabolism.

Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice
Science 367, 6481, eaaw8429, 2020

Confirmation of second meal effect of barley bread
Significant difference after 60 minutes after meal

Consumption of a meal containing refined barley flour bread is associated with a lower postprandial blood glucose concentration following a second meal than one containing refined wheat flour bread in healthy Japanese: a randomized control trial
Nutrition 72, 110637, 2020

BARLEYmax's dietary fibers are fermented in a wide area of the colon
Contributes to the improvement of intestinal microbiota

Effects of BARLEYmax and high-β-glucan barley line on short-chain fatty acids production and microbiota from the cecum to the distal colon in rats
PLoS One 14, 6, e0218118, 2019

Barley tea slows skin temperature drop in air-conditioned rooms

Roasted Barley Extract (Mugicha) Containing Cyclo(d-Phe-l-Pro) Prevents a Decrease in Skin Temperature in Cold Conditions: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study
J Nutr Sci Vitaminol 65, 90–3, 2019

Barley, with or without Prevotella, contributes to improved glucose tolerance
Prevotella/Bacteroides ratio does not determine responder status

Abundance of gut Prevotella at baseline and metabolic response to barley prebiotics
Eur J Nutr 25 Jul 2018

Barley beta-glucan increases Actinobacteria, including Bifidobacterium. Increased short-chain fatty acids and improved metabolism.

Barley β-glucan improves metabolic condition via short-chain fatty acids produced by gut microbial fermentation in high fat diet fed mice
PLoS One 13, e0196579, 2018